Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 3/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.46 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624556 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTCTSSCTSKMME | |
| SCHEMBL18248052 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTCTSSCTSKMME | |
| SCHEMBL1401223 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTCTSSCTSKMME | |
| SCHEMBL8911125 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MAPTCTSSCTSKMME | |
| SCHEMBL2476924 | 0.92 | MMP13 (0.46) | ALDH1A1MAPTCTSSCTSKACE | |
| SCHEMBL1401042 | 0.92 | MMP13 (0.46) | ALDH1A1MAPTCTSSCTSKACE | |
| SCHEMBL65502 | 0.92 | MMP13 (0.46) | ALDH1A1MAPTCTSSCTSKACE | |
| SCHEMBL28520356 | 0.92 | MMP13 (0.54) | PPARGPPARAMMP13ITGB3ITGA2B | |
| SCHEMBL28520354 | 0.92 | MMP13 (0.54) | PPARGPPARAMMP13ITGB3ITGA2B | |
| SCHEMBL31407294 | 0.89 | CTSB (0.50) | ALDH1A1MAPTCTSSCTSKMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300247-B | Teixobactin analogue and application thereof | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-112300247-A | Teixobactin analogue and application thereof | 广东东阳光药业有限公司 | 2021-02-02 | — | — | CN | disclosed |