Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | VEGFA | P15692 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13333662 | 0.86 | VEGFA (0.48) | NR1H2VEGFAEGLN1MGLLALDH1A1 | |
| SCHEMBL17152793 | 0.85 | MTNR1B (0.44) | ACHENR1H2VEGFAEGLN1DRD2 | |
| SCHEMBL17154922 | 0.84 | ACHE (0.39) | ACHERAD52GFERNR1H2VEGFA | |
| SCHEMBL9883952 | 0.82 | ALDH1A1 (0.48) | TACR1ALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9610831 | 0.81 | LMNA (0.53) | VEGFAEGLN1DRD2DRD4ALDH1A1 | |
| SCHEMBL12732683 | 0.81 | LMNA (0.53) | VEGFAEGLN1DRD2DRD4ALDH1A1 | |
| SCHEMBL17153216 | 0.81 | ACHE (0.37) | ACHERAD52GFERNR1H2VEGFA | |
| SCHEMBL17153222 | 0.81 | ACHE (0.37) | ACHERAD52GFERNR1H2VEGFA | |
| SCHEMBL17152957 | 0.77 | ALDH1A1 (0.42) | DRD2DRD4ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL13558227 | 0.76 | ALDH1A1 (0.42) | TACR1ALDH1A1MAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080279768-A1 | Bifunctional Metal Chelating Conjugates | MALLINCKRODT LLC | 2008-11-13 | — | — | US | disclosed |
| US-20080279768-A1 | Bifunctional Metal Chelating Conjugates | MALLINCKRODT LLC | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080279768-A1 | Bifunctional Metal Chelating Conjugates | SLC30A5, SLC39A3, SLC30A6 | ACHE 2560/4885RAD52 1128/4885GFER 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.