Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14543420 | 0.72 | RXRA (0.53) | LMNA | |
| SCHEMBL27541398 | 0.72 | NFE2L2 (0.75) | NFE2L2 | |
| SCHEMBL18185663 | 0.70 | HSD11B1 (0.54) | NFE2L2MEN1KMT2ATDP1 | |
| SCHEMBL7027842 | 0.70 | TRPA1 (0.58) | NFE2L2LMNA | |
| SCHEMBL3842854 | 0.69 | ELANE (0.36) | NFE2L2LMNA | |
| SCHEMBL3842857 | 0.69 | ELANE (0.36) | NFE2L2LMNA | |
| SCHEMBL778142 | 0.68 | TDP1 (0.45) | NFE2L2TDP1 | |
| SCHEMBL778141 | 0.68 | TDP1 (0.45) | NFE2L2TDP1 | |
| SCHEMBL6725286 | 0.66 | PNMT (0.41) | NFE2L2 | |
| SCHEMBL16934143 | 0.66 | NFE2L2 (0.66) | NFE2L2MEN1LMNAKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5445764-A | Based on derivatives of m-difluorobenzene; low viscosity; stability; broad mesophase range; good optical and dielectric anisotropy; specific resistance; matrix and supertwist displays | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-08-29 | — | — | US | disclosed |