Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14016347 | 0.87 | MEN1 (0.46) | MEN1KMT2AALDH1A1TSHRMGAM | |
| SCHEMBL15451360 | 0.83 | MEN1 (0.43) | MEN1KMT2AALDH1A1TSHRMGAM | |
| SCHEMBL2638021 | 0.78 | MMP8 (0.43) | MEN1KMT2AALDH1A1TSHRMGAM | |
| SCHEMBL28512089 | 0.77 | MEN1 (0.43) | MEN1KMT2AALDH1A1TSHRMGAM | |
| SCHEMBL4382740 | 0.76 | MEN1 (0.37) | MEN1KMT2AALDH1A1TSHRMGAM | |
| SCHEMBL28464690 | 0.76 | MEN1 (0.41) | MEN1KMT2AALDH1A1TSHRMGAM | |
| SCHEMBL1963 | 0.74 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1TSHRMGAM | |
| SCHEMBL4377134 | 0.74 | MMP8 (0.36) | MEN1KMT2AALDH1A1TSHRMGAM | |
| SCHEMBL4380430 | 0.74 | MEN1 (0.36) | MEN1KMT2AALDH1A1TSHRMGAM | |
| SCHEMBL15437624 | 0.73 | MEN1 (0.35) | MEN1KMT2AALDH1A1TSHRMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895769-B2 | Silicon-containing carboxylic acid derivative | KEMPHYS LTD. (JP) | 2014-11-25 | — | — | US | disclosed |
| EP-2700645-A1 | SILICON-CONTAINING CARBOXYLIC ACID DERIVATIVE | Research Foundation Itsuu Laboratory (JP) | 2014-02-26 | — | — | EP | disclosed |
| US-20140031575-A1 | SILICON-CONTAINING CARBOXYLIC ACID DERIVATIVE | KEMPHYS LTD. (JP) | 2014-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031575-A1 | SILICON-CONTAINING CARBOXYLIC ACID DERIVATIVE | CA6, CCR6, CXCR6 | MEN1 1280/4885KMT2A 861/4885ALDH1A1 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.