Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605039 | 0.86 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL5605556 | 0.77 | HDAC6 (0.62) | POLB | |
| SCHEMBL27575615 | 0.76 | ERN1 (0.40) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL5605301 | 0.75 | MMP12 (0.52) | CHEK1 | |
| SCHEMBL13892837 | 0.74 | MMP12 (0.47) | KDM4EPOLBHDAC1HDAC2HDAC3 | |
| SCHEMBL3081682 | 0.73 | CHEK1 (0.62) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL4559856 | 0.72 | AR (0.52) | CHEK1CHEK2HDAC1HDAC2HDAC3 | |
| SCHEMBL6142324 | 0.72 | MMP12 (0.47) | CHEK1CHEK2 | |
| SCHEMBL28110998 | 0.72 | KCNH2 (0.55) | KDM4EALDH1A1GAAMAPTHPGD | |
| Carbamic Acid SCHEMBL26695414 | 0.72 | HPGDS (0.54) | KDM4EALDH1A1GAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1588173-B1 | AFFINITY FISHING FOR LIGANDS AND PROTEINS RECEPTORS | NOVO NORDISK AS (DK) | 2008-11-26 | — | — | EP | disclosed |