Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A6 | Q9BXS9 | 2/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3822762 | 0.84 | SMN1; SMN2 (0.49) | KMT2AKDM4EAHRCYP1A2SMN1; SMN2 | |
| SCHEMBL14019446 | 0.78 | TARBP2 (0.46) | MEN1KMT2AKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL3823043 | 0.77 | MAPT (0.48) | KDM4EAHRCYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL4887366 | 0.77 | SLC26A6 (0.46) | SLC26A6KMT2ACYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL892287 | 0.76 | SLC26A6 (0.52) | SLC26A6MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL14019449 | 0.76 | HDAC4 (0.42) | KDM4EAHRCYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL3822181 | 0.74 | FBP1 (0.41) | MEN1KMT2AKDM4EAHRCYP1A2 | |
| SCHEMBL11622665 | 0.72 | TARBP2 (0.63) | KMT2AKDM4ESMN1; SMN2NPC1MAPT | |
| SCHEMBL3821702 | 0.72 | SMN1; SMN2 (0.48) | KMT2AKDM4ESMN1; SMN2NPC1MAPT | |
| SCHEMBL13678351 | 0.72 | FBP1 (0.37) | KDM4EAHRCYP1A2SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | PAH, TST, MPST | SLC26A6 110/4885PSEN1 1046/4885PSEN2 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.