Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15637303 | 0.81 | SMN1; SMN2 (0.58) | HPGDSMN1; SMN2LMNACA1CA2 | |
| SCHEMBL9680727 | 0.78 | SMN1; SMN2 (0.60) | HPGDSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL14022033 | 0.76 | LMNA (0.65) | HPGDSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10243312 | 0.72 | L3MBTL1 (0.48) | HPGDSMN1; SMN2LMNACA1CA2 | |
| SCHEMBL10244994 | 0.72 | CA1 (0.53) | HPGDSMN1; SMN2LMNACA1CA2 | |
| SCHEMBL17029843 | 0.72 | CA1 (0.53) | HPGDSMN1; SMN2LMNACA1CA2 | |
| SCHEMBL19658746 | 0.72 | SMN1; SMN2 (0.56) | HPGDSMN1; SMN2LMNACA1CA2 | |
| SCHEMBL10244611 | 0.71 | HPGD (0.49) | HPGDSMN1; SMN2LMNACA1CA2 | |
| SCHEMBL335035 | 0.71 | CA1 (0.53) | HPGDSMN1; SMN2LMNACA1CA2 | |
| SCHEMBL6155512 | 0.71 | CA1 (0.56) | HPGDSMN1; SMN2LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135386-A1 | CHIRAL LIGANDS OF THE N-HETEROCYCLIC CARBENE TYPE FOR ASYMMETRICAL CATALYSIS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2008-11-13 | — | — | WO | disclosed |