Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 4/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ATF4 | P18848 | 3/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8263299 | 0.85 | MCL1 (0.48) | ALDH1A1VCP | |
| SCHEMBL4902486 | 0.85 | ADRB3 (0.65) | ADRB3ADRB1KDM4EMAPTMAPK1 | |
| SCHEMBL4899642 | 0.85 | ADRB3 (0.65) | ADRB3ADRB1KDM4EMAPTMAPK1 | |
| SCHEMBL8263806 | 0.85 | ADRB3 (0.65) | ADRB3ADRB1KDM4EMAPTMAPK1 | |
| SCHEMBL4894572 | 0.84 | MEN1 (0.58) | ADRB3ADRB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL4894557 | 0.84 | MEN1 (0.58) | ADRB3ADRB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL8183056 | 0.81 | CYP3A4 (0.56) | ALDH1A1KDM4EMEN1MITFMAPT | |
| SCHEMBL4656378 | 0.78 | GPR119 (0.52) | ADRB3ADRB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL8191425 | 0.78 | HRH1 (0.59) | ADRB3ADRB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL4920538 | 0.78 | ALDH1A1 (0.49) | ADRB3ADRB1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255134-A1 | Cardiotonic Compounds With Inhibitory Activity Against Beta-Adrenergic Receptors And Phosphodiesterase | ARTESIAN THERAPEUTICS, INC. (US) | 2008-10-16 | — | — | US | disclosed |
| US-20080255134-A1 | Cardiotonic Compounds With Inhibitory Activity Against Beta-Adrenergic Receptors And Phosphodiesterase | ARTESIAN THERAPEUTICS, INC. (US) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255134-A1 | Cardiotonic Compounds With Inhibitory Activity Against Beta-Adrenergic Receptors And Phosphodiesterase | ADRB3, PDE3A, ADRB1 | ADRB3 1/4885ADRB1 3/4885ALDH1A1 1034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.