Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.55 |
| ▸ | ACLY | P53396 | 15/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14023341 | 0.91 | SLC22A12 (0.55) | SLC22A12ACLYPDK1PDK2PDK3 | |
| SCHEMBL4890184 | 0.89 | SLC22A12 (0.59) | SLC22A12ACLY | |
| SCHEMBL4893835 | 0.84 | SLC22A12 (0.57) | SLC22A12ACLYPDK1PDK2PDK3 | |
| SCHEMBL4898138 | 0.84 | SLC22A12 (0.57) | SLC22A12ACLYPDK1PDK2PDK3 | |
| SCHEMBL4893777 | 0.83 | SLC22A12 (0.56) | SLC22A12ACLYPDK1PDK2PDK3 | |
| SCHEMBL14023339 | 0.82 | SLC22A12 (0.48) | SLC22A12ACLYPDK1PDK2PDK3 | |
| SCHEMBL14023335 | 0.82 | ACLY (0.42) | SLC22A12ACLY | |
| SCHEMBL4896279 | 0.79 | SLC22A12 (0.52) | SLC22A12ACLYPDK1PDK2PDK3 | |
| SCHEMBL14023343 | 0.76 | ACLY (0.44) | SLC22A12ACLY | |
| SCHEMBL4890245 | 0.73 | MCL1 (0.54) | SLC22A12ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255240-A1 | Sulfonamide Derivatives | NOVO NORDISK A/S (DK) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255240-A1 | Sulfonamide Derivatives | FABP4, SQOR, CS | SLC22A12 1558/4885ACLY 167/4885PDK1 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.