Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22823029 | 0.82 | SMN1; SMN2 (0.70) | POLBALDH1A1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL10192030 | 0.82 | ALDH1A1 (0.70) | POLBALDH1A1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL763452 | 0.81 | HTT (0.78) | LMNAALDH1A1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL12459935 | 0.81 | CD274 (0.79) | LMNAALDH1A1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL10318171 | 0.80 | POLB (0.69) | LMNAPOLBALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL23139667 | 0.78 | ALDH1A1 (0.64) | LMNAALDH1A1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL9926499 | 0.78 | ALDH1A1 (0.67) | POLBTP53ALDH1A1TSHRKDM4E | |
| SCHEMBL15485296 | 0.78 | CD274 (0.62) | POLBTP53ALDH1A1TSHRKDM4E | |
| SCHEMBL17652655 | 0.78 | LMNA (0.68) | LMNAPOLBTP53ALDH1A1TSHR | |
| SCHEMBL15484809 | 0.78 | ALDH1A1 (0.79) | LMNAPOLBTP53ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140420-A2 | PYRIMIDINE DERIVATIVES | S*BIO PTE LTD (SG) | 2008-11-20 | — | — | WO | disclosed |