Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | PHLPP2 | Q6ZVD8 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.41 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.41 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.41 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ATIC | P31939 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13879698 | 0.86 | PHLPP2 (0.45) | PTPN11PHLPP2ALDH1A1KDM4EHPGD | |
| SCHEMBL12028003 | 0.76 | ENPP2 (0.52) | PTPN11PHLPP2ALDH1A1KDM4EHPGD | |
| SCHEMBL12028010 | 0.75 | PHLPP2 (0.55) | PTPN11PHLPP2ALDH1A1KDM4EHPGD | |
| SCHEMBL14001684 | 0.75 | MAPT (0.35) | PTPN11PHLPP2ALDH1A1KDM4EHPGD | |
| SCHEMBL13811608 | 0.73 | S1PR3 (0.44) | PTPN11PHLPP2ALDH1A1KDM4EHPGD | |
| SCHEMBL6125350 | 0.73 | S1PR3 (0.47) | PTPN11PHLPP2ALDH1A1KDM4EHPGD | |
| SCHEMBL15958581 | 0.72 | PTPN11 (0.54) | PTPN11PHLPP2ALDH1A1KDM4EHPGD | |
| SCHEMBL13879699 | 0.71 | ENPP2 (0.48) | PTPN11PHLPP2ALDH1A1KDM4EHPGD | |
| SCHEMBL14580409 | 0.71 | PTPN11 (0.56) | PTPN11PHLPP2ALDH1A1KDM4EHPGD | |
| SCHEMBL12028007 | 0.71 | ALDH1A1 (0.46) | PTPN11PHLPP2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7445822-B2 | Azo compounds and dye-type polarizing films or plates containing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2008-11-04 | — | — | US | disclosed |
| US-20080094549-A1 | Azo Compounds And Dye-Type Polarizing Films Or Plates Containing The Same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080094549-A1 | Azo Compounds And Dye-Type Polarizing Films Or Plates Containing The Same | CRY1, SCO2, SPR | PTPN11 1066/4885PHLPP2 695/4885ALDH1A1 1256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.