Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 12/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028701 | 0.93 | ALDH1A3 (0.51) | ALDH1A3ALDH1A1ALDH1A2SLC2A1NR4A2 | |
| SCHEMBL8866583 | 0.86 | ALDH1A1 (0.62) | ALDH1A3ALDH1A1ALDH1A2SLC2A1NR4A2 | |
| SCHEMBL2127102 | 0.86 | NPC1 (0.60) | ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1 | |
| SCHEMBL2632253 | 0.86 | NPC1 (0.60) | ALDH1A3ALDH1A1ALDH1A2SLC2A1NPC1 | |
| SCHEMBL2126832 | 0.85 | ALDH1A3 (0.55) | ALDH1A3ALDH1A1ALDH1A2NPC1RAB9A | |
| SCHEMBL14046610 | 0.84 | ALDH1A3 (0.56) | ALDH1A3ALDH1A1ALDH1A2SLC2A1NR4A2 | |
| SCHEMBL8865941 | 0.82 | ALDH1A1 (0.66) | ALDH1A3ALDH1A1ALDH1A2NR4A2NPC1 | |
| SCHEMBL2128034 | 0.79 | APP (0.46) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL2632304 | 0.79 | APP (0.46) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL14028705 | 0.77 | ALDH1A1 (0.41) | ALDH1A3ALDH1A1SLC2A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432278-B2 | Dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2008-10-07 | — | — | US | disclosed |