Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.60 |
| ▸ | RAB9A | P51151 | 11/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | KDM5A | P29375 | 1/20 | 0.60 |
| ▸ | KDM5C | P41229 | 1/20 | 0.60 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127102 | 1.00 | NPC1 (0.60) | NPC1ALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL2126832 | 0.88 | ALDH1A3 (0.55) | NPC1ALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL14046610 | 0.87 | ALDH1A3 (0.56) | NPC1ALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL14028702 | 0.86 | ALDH1A3 (0.58) | NPC1ALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL2632304 | 0.84 | APP (0.46) | NPC1ALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL2128034 | 0.84 | APP (0.46) | NPC1ALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8866583 | 0.84 | ALDH1A1 (0.62) | NPC1ALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL8865941 | 0.82 | ALDH1A1 (0.66) | NPC1ALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL14028701 | 0.80 | ALDH1A3 (0.51) | NPC1ALDH1A1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL2129032 | 0.78 | ALDH1A1 (0.73) | NPC1ALDH1A1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399476-B2 | Imidazo[1,2-a]pyridines and their use as pharmaceuticals | SANOFI (FR) | 2013-03-19 | — | — | US | disclosed |
| US-8399476-B2 | Imidazo[1,2-a]pyridines and their use as pharmaceuticals | SANOFI (FR) | 2013-03-19 | — | — | US | disclosed |
| EP-2129375-B1 | IMIDAZO[1,2-A]PYRIDINES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2012-04-25 | — | — | EP | disclosed |
| US-20100113412-A1 | IMIDAZO[1,2-a]PYRIDINES AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (FR) | 2010-05-06 | — | — | US | disclosed |
| US-20100113412-A1 | IMIDAZO[1,2-a]PYRIDINES AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (FR) | 2010-05-06 | — | — | US | disclosed |
| WO-2008104278-A1 | IMIDAZO[1,2-A] PYRIDINES AND THEIR USE AS PHARMACEUTICALS | SANOFI-AVENTIS (FR) | 2008-09-04 | — | — | WO | disclosed |
| EP-1964840-A1 | Imidazo[1,2-a]pyridines and their use as pharmaceuticals | sanofi-aventis (FR) | 2008-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113412-A1 | IMIDAZO[1,2-a]PYRIDINES AND THEIR USE AS PHARMACEUTICALS | NOS1, PTGIS, NOS2 | NPC1 2959/4885ALDH1A1 1286/4885RAB9A 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.