Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 2/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14034247 | 0.89 | CNR1 (0.43) | PABPC1EIF4HMEN1KMT2AL3MBTL1 | |
| SCHEMBL14033360 | 0.84 | L3MBTL1 (0.48) | PABPC1EIF4HMEN1KMT2AL3MBTL1 | |
| SCHEMBL14033971 | 0.76 | L3MBTL1 (0.47) | MEN1KMT2AL3MBTL1KDM4EMAPT | |
| SCHEMBL3749378 | 0.75 | MAPT (0.48) | PABPC1EIF4HMEN1KMT2AL3MBTL1 | |
| SCHEMBL30575775 | 0.75 | CYP2C19 (0.47) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL14033462 | 0.75 | CYP2C19 (0.47) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL27335432 | 0.71 | MAPT (0.44) | MEN1KMT2AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL14034054 | 0.71 | LMNA (0.48) | L3MBTL1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL30994907 | 0.71 | MAPT (0.52) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL22049618 | 0.71 | MAPT (0.52) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432268-B2 | 17β-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | SCHERING CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432268-B2 | 17β-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | SCHERING CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |