Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | EIF4A1 | P60842 | 5/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14035529 | 0.85 | DHODH (0.54) | DHODHPSMB5TRPV1CTRCEIF4A1 | |
| SCHEMBL12708293 | 0.82 | KDM4E (0.42) | DHODHTACR3 | |
| SCHEMBL16229566 | 0.76 | BCHE (0.43) | DHODHPSMB5TACR3 | |
| SCHEMBL10155099 | 0.76 | KDM4E (0.56) | — | |
| SCHEMBL12201040 | 0.75 | ESR1 (0.53) | DHODH | |
| SCHEMBL9705061 | 0.75 | DHODH (0.52) | DHODHPSMB5CTRCHSD11B1ADORA1 | |
| SCHEMBL14623967 | 0.75 | KDM4E (0.55) | TACR3ADORA1 | |
| SCHEMBL1256551 | 0.75 | ACHE (0.61) | DHODHTACR3 | |
| SCHEMBL16234057 | 0.74 | DHODH (0.56) | DHODHPSMB5TRPV1CTRCEIF4A1 | |
| SCHEMBL22827977 | 0.74 | DHODH (0.56) | DHODHPSMB5TRPV1CTRCEIF4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505945-B1 | SUBSTITUTED CYCLOALKYL P1' HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-11-05 | — | — | EP | disclosed |