Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14035489 | 0.85 | DHODH (0.56) | DHODHPSMB5TRPV1HSD11B1TACR3 | |
| SCHEMBL13541765 | 0.76 | ALDH1A1 (0.55) | PSMB5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9705061 | 0.76 | DHODH (0.52) | DHODHPSMB5HSD11B1MAPTMEN1 | |
| SCHEMBL951744 | 0.76 | MAPT (0.65) | DHODHALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL24755295 | 0.76 | HSD11B1 (0.59) | DHODHPSMB5TRPV1HSD11B1ALDH1A1 | |
| SCHEMBL14319678 | 0.75 | ALDH1A1 (0.50) | PSMB5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL22827977 | 0.75 | DHODH (0.56) | DHODHPSMB5TRPV1HSD11B1ALDH1A1 | |
| SCHEMBL16234057 | 0.75 | DHODH (0.56) | DHODHPSMB5TRPV1HSD11B1ALDH1A1 | |
| SCHEMBL6859623 | 0.74 | ALDH1A1 (0.63) | DHODHALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30946935 | 0.74 | ALDH1A1 (0.63) | DHODHALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505945-B1 | SUBSTITUTED CYCLOALKYL P1' HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-11-05 | — | — | EP | disclosed |