Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27558053 | 1.00 | LMNA (0.46) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL21344297 | 1.00 | LMNA (0.46) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL13347915 | 0.89 | CHRNB2 (0.45) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL10068167 | 0.83 | CYP1A2 (0.44) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL21098353 | 0.81 | CHRNB2 (0.44) | LMNAKDM4ECHRNB2CHRNA4CHRM2 | |
| SCHEMBL19853430 | 0.81 | CHRNB2 (0.44) | LMNAMEN1KMT2ACHRNB2CHRNA4 | |
| SCHEMBL6841404 | 0.80 | LMNA (0.43) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28474276 | 0.80 | CHRNB2 (0.42) | LMNAKDM4ECHRNB2CHRNA4CHRM2 | |
| SCHEMBL9681883 | 0.79 | SMN1; SMN2 (0.49) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL19651542 | 0.79 | LMNA (0.43) | LMNAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3855241-B1 | CONTACT LENS TREATMENT SOLUTION | NOF CORP (JP) | 2024-01-24 | — | — | EP | disclosed |
| EP-3855241-A1 | CONTACT LENS TREATMENT SOLUTION | NOF Corporation (JP) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020059593-A1 | CONTACT LENS TREATMENT SOLUTION | 日油株式会社 | 2020-03-26 | — | — | WO | disclosed |
| US-20170342046-A1 | Fatty Acid Cysteine-Based Conjugates and Their Use in Treating Medical Disorders | CATABASIS PHARMACEUTICALS, INC. | 2017-11-30 | — | — | US | disclosed |
| US-9777245-B2 | Methods of fractionating metathesized triacylglycerol polyols and uses thereof | TRENT UNIVERSITY (CA) | 2017-10-03 | — | — | US | disclosed |
| US-9408919-B2 | Biodegradable polymer—bioactive moiety conjugates | POLYACTIVA PTY LTD. (AU) | 2016-08-09 | — | — | US | disclosed |
| US-8652568-B2 | Coating composition | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-02-18 | — | — | US | disclosed |
| US-8652568-B2 | Coating composition | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-02-18 | — | — | US | disclosed |
| US-20140046018-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | POLYACTIVA PTY LTD. (AU) | 2014-02-13 | — | — | US | disclosed |
| US-8535655-B2 | Biodegradable polymer—bioactive moiety conjugates | POLYACTIVA PTY LTD. (AU) | 2013-09-17 | — | — | US | disclosed |
| US-20120059107-A1 | COATING COMPOSITION | DOW GLOBAL TECHNOLOGIES LLC | 2012-03-08 | — | — | US | disclosed |
| US-20120059107-A1 | COATING COMPOSITION | DOW GLOBAL TECHNOLOGIES LLC | 2012-03-08 | — | — | US | disclosed |
| EP-2426158-A1 | A coating composition | Dow Global Technologies LLC (US) | 2012-03-07 | — | — | EP | disclosed |
| US-20110243884-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | THE BIONICS INSTITUTE OF AUSTRALIA (AU) | 2011-10-06 | — | — | US | disclosed |
| EP-1513527-A1 | PRODRUGS OF IMIDAZOLE DERIVATIVES, FOR USE AS PROTON PUMP INHIBITORS IN THE TREATMENT OF E.G. PEPTIC ULCERS | Takeda Pharmaceutical Company Limited (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003105845-A1 | PRODRUGS OF IMIDAZOLE DERIVATIVES, FOR USE AS PROTON PUMP INHIBITORS IN THE TREATMENT OF E.G. PEPTIC ULCERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342046-A1 | Fatty Acid Cysteine-Based Conjugates and Their Use in Treating Medical Disorders | CPT2, FABP1, ACAA2 | LMNA 3607/4885KDM4E 4176/4885DUSP3 2700/4885 |
| US-20140046018-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | BMP2, MKI67, FGF2 | LMNA 2564/4885KDM4E 2847/4885DUSP3 1804/4885 |
| US-20110243884-A1 | BIODEGRADABLE POLYMER - BIOACTIVE MOIETY CONJUGATES | BMP2, MKI67, FGF2 | LMNA 2564/4885KDM4E 2847/4885DUSP3 1804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.