SCHEMBL14036342

SCHEMBL14036342

Cc1cc(C)cc(-c2cccc(-c3cc(C)cc(-c4ccccc4)c3)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.52
RXRA P19793 1/20 0.48
RXRB P28702 1/20 0.48
ACHE P22303 1/20 0.46
ALDH1A1 P00352 1/20 0.45
KMO O15229 1/20 0.45
DHODH Q02127 3/20 0.44
NPC1 O15118 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP1A1 P04798 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP1B1 Q16678 2/20 0.43
CYP2E1 P05181 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C8 P10632 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2A6 P11509 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27948002 1.00 MAOA (0.52) MAOARXRARXRBACHEALDH1A1
Hydrogen Sulfide SCHEMBL27621093 0.98 MAOA (0.50) MAOARXRARXRBACHEALDH1A1
SCHEMBL23518713 0.97 MAOA (0.48) MAOARXRARXRBACHEALDH1A1
SCHEMBL14036343 0.97 MAOA (0.48) MAOARXRARXRBACHEALDH1A1
SCHEMBL28376833 0.95 MAOA (0.56) MAOAACHEALDH1A1KMODHODH
SCHEMBL9083578 0.93 ACHE (0.57) MAOARXRARXRBACHEALDH1A1
Bromide SCHEMBL28655778 0.92 MAOA (0.54) MAOAACHEALDH1A1KMODHODH
SCHEMBL2837502 0.92 ALDH1A1 (0.53) MAOARXRARXRBACHEALDH1A1
SCHEMBL1830671 0.92 RXRA (0.54) MAOARXRARXRBACHEALDH1A1
SCHEMBL24444327 0.92 ALDH1A1 (0.53) MAOARXRARXRBACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1988143-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, WHITE LIGHT EMITTING ELEMENT, DISPLAY DEVICE AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2008-11-05 EP disclosed