Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036397 | 0.90 | SMN1; SMN2 (0.45) | ALDH1A1POLBNPSR1GAADHFR | |
| SCHEMBL18768220 | 0.78 | LMNA (0.38) | ALDH1A1POLBNPSR1GAAL3MBTL1 | |
| SCHEMBL11230722 | 0.77 | ESR1 (0.42) | MAPTKMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL14015795 | 0.77 | THRB (0.51) | DHFRTP53L3MBTL1MAPTHPGD | |
| SCHEMBL171049 | 0.75 | ALDH1A1 (0.44) | ALDH1A1POLBNPSR1GAADHFR | |
| SCHEMBL12161010 | 0.75 | SMN1; SMN2 (0.41) | ALDH1A1POLBNPSR1GAAL3MBTL1 | |
| SCHEMBL170572 | 0.75 | ALDH1A1 (0.47) | ALDH1A1POLBNPSR1GAAKDM4E | |
| SCHEMBL13602320 | 0.75 | CYP1A2 (0.47) | ALDH1A1POLBNPSR1GAAKDM4E | |
| SCHEMBL13475559 | 0.74 | ESR1 (0.49) | ALDH1A1NPSR1GAAMAPTHPGD | |
| SCHEMBL22138548 | 0.74 | AKR1B1 (0.38) | ALDH1A1POLBNPSR1DHFRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020185494-A1 | BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION WITH CHAIN TRANSFER CAPABILITY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-09-17 | — | — | WO | disclosed |
| WO-2020131566-A1 | BIARYL PHENOXY GROUP IV TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-06-25 | — | — | WO | disclosed |