SCHEMBL14036456

SCHEMBL14036456

Cc1ccc(N(c2ccccc2)c2ccc(C=Cc3cc(C#N)ccc3C#N)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.40
NFE2L2 Q16236 2/20 0.38
NR1H3 Q13133 1/20 0.38
TRPM8 Q7Z2W7 2/20 0.37
PRKCQ Q04759 2/20 0.37
PRKCD Q05655 2/20 0.37
ALDH1A1 P00352 3/20 0.37
CYP2A6 P11509 1/20 0.37
FGF23 Q9GZV9 1/20 0.36
RELA Q04206 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
HPGD P15428 2/20 0.35
ALOX12 P18054 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
SNCA P37840 1/20 0.34
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14436657 0.88 APP (0.44) APPNFE2L2TRPM8PRKCQPRKCD
SCHEMBL14436656 0.88 APP (0.44) APPNFE2L2TRPM8PRKCQPRKCD
SCHEMBL12310016 0.88 NR1H3 (0.38) APPNR1H3PRKCQPRKCDALDH1A1
SCHEMBL10074799 0.87 TRPA1 (0.46) APPNFE2L2TRPM8ALDH1A1RELA
SCHEMBL10074806 0.84 CA1 (0.34) APPNFE2L2NR1H3PRKCQPRKCD
SCHEMBL14437326 0.84 APP (0.41) APPNFE2L2TRPM8PRKCQPRKCD
SCHEMBL22017427 0.82 NFE2L2 (0.41) APPNFE2L2PRKCQPRKCDALDH1A1
SCHEMBL14436658 0.82 NFE2L2 (0.41) APPNFE2L2PRKCQPRKCDALDH1A1
SCHEMBL12310015 0.82 NR1H3 (0.36) NR1H3PRKCQPRKCDALDH1A1CYP2A6
SCHEMBL5862346 0.82 NFE2L2 (0.40) APPNFE2L2ALDH1A1HPGDSNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080292904-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2008-11-27 US disclosed