SCHEMBL22017427

SCHEMBL22017427

Cc1ccc(N(c2ccc(C)cc2)c2ccc(/C=C/c3cc(C#N)c(/C=C/c4ccc(N(c5ccc(C)cc5)c5ccc(C)cc5)cc4)cc3C#N)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 7/20 0.41
PTGS1 P23219 2/20 0.39
PTGS2 P35354 2/20 0.39
ALOX5 P09917 1/20 0.39
KDM4E B2RXH2 1/20 0.38
FGF23 Q9GZV9 1/20 0.37
RELA Q04206 1/20 0.37
APP P05067 4/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36
TUBA3E Q6PEY2 1/20 0.36
TUBA1A Q71U36 1/20 0.36
TUBA1C Q9BQE3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14436658 1.00 NFE2L2 (0.41) NFE2L2PTGS1PTGS2ALOX5KDM4E
SCHEMBL14436657 0.94 APP (0.44) NFE2L2KDM4EFGF23RELAAPP
SCHEMBL14436656 0.94 APP (0.44) NFE2L2KDM4EFGF23RELAAPP
SCHEMBL823205 0.90 NFE2L2 (0.49) NFE2L2PTGS1PTGS2ALOX5KDM4E
SCHEMBL14437326 0.89 APP (0.41) NFE2L2PTGS1PTGS2ALOX5KDM4E
SCHEMBL14436652 0.86 RELA (0.50) NFE2L2PTGS2ALOX5KDM4ERELA
SCHEMBL9915842 0.85 APP (0.46) KDM4ERELAAPPPRKCQPRKCD
SCHEMBL7716038 0.85 APP (0.46) KDM4ERELAAPPPRKCQPRKCD
SCHEMBL14462119 0.84 PKM (0.34) NFE2L2ALDH1A1CYP2A6
SCHEMBL13599895 0.83 NFE2L2 (0.49) NFE2L2PTGS1PTGS2ALOX5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220140022-A1 ORGANIC LIGHT EMITTING DEVICE, DISPLAY APPARATUS, PHOTOELECTRIC CONVERSION APPARATUS, ILLUMINATION APPARATUS, AND MOVING OBJECT CANON KK (JP) 2022-05-05 US disclosed
US-11257878-B2 Organic light emitting device, display apparatus, photoelectric conversion apparatus, illumination apparatus, and moving object CANON KABUSHIKI KAISHA (JP) 2022-02-22 US disclosed
US-20200161387-A1 ORGANIC LIGHT EMITTING DEVICE, DISPLAY APPARATUS, PHOTOELECTRIC CONVERSION APPARATUS, ILLUMINATION APPARATUS, AND MOVING OBJECT CANON KABUSHIKI KAISHA (JP) 2020-05-21 US disclosed