Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 5/20 | 0.39 |
| ▸ | GSK3B | P49841 | 5/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 4/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036554 | 0.93 | USP30 (0.44) | USP30TP53MAPTSMN1; SMN2ROCK2 | |
| SCHEMBL14036547 | 0.85 | USP30 (0.45) | USP30TP53MAPTSMN1; SMN2ROCK2 | |
| SCHEMBL14036635 | 0.78 | TP53 (0.39) | TP53MAPTSMN1; SMN2AAK1UBE2M | |
| SCHEMBL14036548 | 0.77 | UBE2M (0.43) | TP53MAPTSMN1; SMN2UBE2MDCUN1D1 | |
| SCHEMBL14036793 | 0.77 | UBE2M (0.35) | TP53MAPTSMN1; SMN2ROCK2UBE2M | |
| SCHEMBL14036573 | 0.72 | TP53 (0.41) | TP53MAPTSMN1; SMN2AAK1UBE2M | |
| SCHEMBL14036556 | 0.71 | UBE2M (0.40) | TP53MAPTROCK2UBE2MDCUN1D1 | |
| SCHEMBL23199996 | 0.70 | USP30 (0.47) | USP30TP53MAPTSMN1; SMN2ROCK2 | |
| SCHEMBL14036686 | 0.69 | EP300 (0.38) | MAPT | |
| SCHEMBL14036808 | 0.68 | PSEN1 (0.42) | USP30TP53MAPTUBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |