Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LDLR | P01130 | 2/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036693 | 0.88 | PSEN1 (0.39) | ALDH1A1RAB9ARET | |
| SCHEMBL14036775 | 0.73 | PSEN1 (0.50) | — | |
| SCHEMBL14036793 | 0.73 | UBE2M (0.35) | ALDH1A1MAPT | |
| SCHEMBL14036575 | 0.71 | DDX3X (0.40) | ALDH1A1RAB9AMAPTNPSR1DDX3X | |
| SCHEMBL14036550 | 0.69 | USP30 (0.44) | MAPT | |
| SCHEMBL14036808 | 0.69 | PSEN1 (0.42) | MAPT | |
| SCHEMBL757334 | 0.68 | PSEN1 (0.45) | TSHRNPSR1 | |
| SCHEMBL759528 | 0.68 | PSEN1 (0.60) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL14036790 | 0.68 | PSEN1 (0.39) | — | |
| SCHEMBL758919 | 0.67 | PSEN1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |