SCHEMBL14036635 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	TP53	P04637	5/20	0.39

▸	MAPT	P10636	2/20	0.39

▸	SMN1; SMN2	Q16637	1/20	0.39

▸	DDX3X	O00571	1/20	0.39

▸	UBE2M	P61081	10/20	0.39

▸	DCUN1D1	Q96GG9	10/20	0.39

▸	POLB	P06746	1/20	0.36

▸	MEN1	O00255	1/20	0.35

▸	LMNA	P02545	1/20	0.35

▸	KMT2A	Q03164	1/20	0.35

▸	GPR55	Q9Y2T6	1/20	0.35

▸	L3MBTL1	Q9Y468	1/20	0.35

▸	AAK1	Q2M2I8	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14036573	0.95	TP53 (0.41)	TP53MAPTSMN1; SMN2DDX3XUBE2M
SCHEMBL14036632	0.88	TP53 (0.40)	TP53MAPTSMN1; SMN2DDX3XUBE2M
SCHEMBL14036574	0.85	TP53 (0.44)	TP53MAPTSMN1; SMN2DDX3XUBE2M
SCHEMBL14036636	0.84	TP53 (0.42)	TP53MAPTSMN1; SMN2DDX3XUBE2M
SCHEMBL14036575	0.84	DDX3X (0.40)	MAPTDDX3XPOLBLMNAAAK1
SCHEMBL14036560	0.83	TP53 (0.41)	TP53MAPTSMN1; SMN2DDX3XUBE2M
SCHEMBL14036793	0.79	UBE2M (0.35)	TP53MAPTSMN1; SMN2UBE2MDCUN1D1
SCHEMBL14036550	0.78	USP30 (0.44)	TP53MAPTSMN1; SMN2UBE2MDCUN1D1
SCHEMBL14036554	0.76	USP30 (0.44)	TP53MAPTSMN1; SMN2UBE2MDCUN1D1
SCHEMBL757334	0.74	PSEN1 (0.45)	TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008137102-A2	METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR	TORREYPINES THERAPEUTICS, INC. (US)	2008-11-13	—	—	WO	disclosed