Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036690 | 0.87 | GAA (0.43) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL10145745 | 0.87 | NPBWR1 (0.42) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL14036538 | 0.84 | KDM1A (0.57) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL14036780 | 0.83 | KDM4E (0.36) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL5013641 | 0.82 | POLB (0.43) | MEN1KMT2AKDM4EGAAPOLB | |
| SCHEMBL14036774 | 0.81 | GAA (0.51) | MEN1KMT2AKDM4EGAAPOLB | |
| SCHEMBL13184317 | 0.77 | MEN1 (0.47) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL12425507 | 0.76 | POLB (0.56) | MEN1KMT2AKDM4EGAAPOLB | |
| SCHEMBL16200315 | 0.75 | KMT2A (0.58) | MEN1KMT2AKDM4EGAAHTT | |
| SCHEMBL13132346 | 0.75 | MEN1 (0.51) | MEN1KMT2AKDM4EGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |