Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145745 | 0.88 | NPBWR1 (0.42) | KDM4EMEN1KMT2AGAAHTT | |
| SCHEMBL14036621 | 0.83 | MEN1 (0.49) | KDM4EMEN1KMT2AGAAHTT | |
| SCHEMBL14036778 | 0.73 | LMNA (0.52) | KDM4EGAAHTTTDP1CYP1A2 | |
| SCHEMBL14036690 | 0.72 | GAA (0.43) | KDM4EMEN1KMT2AGAAHTT | |
| SCHEMBL14036538 | 0.71 | KDM1A (0.57) | KDM4EMEN1KMT2AGAAHTT | |
| SCHEMBL13132346 | 0.71 | MEN1 (0.51) | KDM4EMEN1KMT2AGAAHTT | |
| SCHEMBL18508767 | 0.71 | MEN1 (0.51) | KDM4EMEN1KMT2AGAAHTT | |
| SCHEMBL14036680 | 0.70 | SLC6A4 (0.43) | GAACYP1A2CYP2D6ADRA2APKM | |
| SCHEMBL14036788 | 0.70 | ADRA1D (0.41) | KDM4EGAAHTTTDP1CYP1A2 | |
| SCHEMBL14036776 | 0.69 | PABPC1 (0.44) | KDM4EMEN1KMT2AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |