Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036621 | 0.87 | MEN1 (0.49) | GAAPOLBGFERKDM1AMAOA | |
| SCHEMBL14036774 | 0.78 | GAA (0.51) | GAAPOLBGFERKDM1AMAOA | |
| SCHEMBL5013641 | 0.76 | POLB (0.43) | GAAPOLBGFERKDM1AMAOA | |
| SCHEMBL10145745 | 0.75 | NPBWR1 (0.42) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14036535 | 0.74 | MEN1 (0.45) | GAAPOLBGFERALDH1A1MEN1 | |
| SCHEMBL12425507 | 0.73 | POLB (0.56) | GAAPOLBGFERALDH1A1MEN1 | |
| SCHEMBL14036538 | 0.72 | KDM1A (0.57) | GAAPOLBKDM1AMAOAMAOB | |
| SCHEMBL14036780 | 0.72 | KDM4E (0.36) | GAAKDM1AMAOAMAOBALDH1A1 | |
| SCHEMBL5014668 | 0.71 | POLB (0.59) | GAAPOLBGFERALDH1A1MEN1 | |
| SCHEMBL14036803 | 0.70 | GAA (0.43) | GAAPOLBGFERALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |