Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12375394 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRERN1SMN1; SMN2GRIA1 | |
| SCHEMBL365835 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHRERN1SMN1; SMN2GRIA1 | |
| SCHEMBL20575666 | 0.78 | LMNA (0.41) | ALDH1A1ERN1POLBMAPTRAB9A | |
| SCHEMBL12961324 | 0.78 | MCL1 (0.34) | ALDH1A1ERN1L3MBTL1MCL1LMNA | |
| SCHEMBL13898962 | 0.78 | NOS3 (0.40) | ALDH1A1TSHRNOS3NOS1NOS2 | |
| SCHEMBL14036539 | 0.77 | GRIA1 (0.44) | ALDH1A1TSHRERN1SMN1; SMN2NOS3 | |
| SCHEMBL5504159 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TSHRERN1SMN1; SMN2GRIA1 | |
| SCHEMBL15250021 | 0.76 | NOS3 (0.39) | ALDH1A1TSHRNOS3NOS1NOS2 | |
| SCHEMBL20022271 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TSHRERN1POLBMAPT | |
| SCHEMBL248719 | 0.75 | ERN1 (0.50) | ALDH1A1TSHRERN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |