Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894210 | 0.87 | ADRA1D (0.55) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL10824976 | 0.87 | ADRA1D (0.55) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL8435468 | 0.87 | ADRA1D (0.55) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL8438758 | 0.87 | ADRA1D (0.55) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL5017334 | 0.86 | PRKCA (0.47) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL5025539 | 0.84 | ADRA1D (0.44) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| Triacetin SCHEMBL17821531 | 0.84 | PRKCA (0.55) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL13449715 | 0.83 | ALDH1A1 (0.53) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL5015534 | 0.81 | USP2 (0.52) | ADRA1DPTAFRHTR1DHTR2CADRA1B | |
| SCHEMBL14017253 | 0.80 | ALDH1A1 (0.50) | ADRA1DPTAFRHTR1DHTR2CADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465876-B1 | LONG CHAIN FATTY ALCOHOL SUBSTITUENTS IN ANTINEOPLASTIC AGENTS | PFAENDLER HANS RUDOLF (DE) | 2008-11-05 | — | — | EP | disclosed |