Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036774 | 0.78 | GAA (0.51) | GAAPOLBGFERKMT2ASMN1; SMN2 | |
| SCHEMBL14036535 | 0.77 | MEN1 (0.45) | GAAPOLBGFERKMT2ACYP1A2 | |
| SCHEMBL5013641 | 0.76 | POLB (0.43) | GAAPOLBGFERKMT2ACYP2D6 | |
| SCHEMBL14036621 | 0.73 | MEN1 (0.49) | GAAPOLBGFERKMT2ASMN1; SMN2 | |
| SCHEMBL12425507 | 0.73 | POLB (0.56) | GAAPOLBGFERKMT2AP2RX3 | |
| SCHEMBL12781719 | 0.71 | P2RX3 (0.47) | GAAPOLBGFERCYP1A2ADRA2A | |
| SCHEMBL5014668 | 0.71 | POLB (0.59) | GAAPOLBGFERKMT2AP2RX3 | |
| SCHEMBL14036690 | 0.70 | GAA (0.43) | GAAPOLBGFERKMT2ASMN1; SMN2 | |
| SCHEMBL20969580 | 0.69 | TAAR1 (0.57) | GAAPOLBGFERCYP1A2HTR2C | |
| SCHEMBL16269630 | 0.69 | CHRM2 (0.68) | POLBKMT2ACYP2D6SMN1; SMN2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |