Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14932642 | 0.84 | ALOX15 (0.37) | MEN1KMT2AMAOAMAOBKDM5A | |
| SCHEMBL25786452 | 0.76 | MEN1 (0.39) | MEN1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL119203 | 0.76 | TSHR (0.50) | MEN1KMT2AL3MBTL1TSHRS1PR1 | |
| Hydrochloric Acid SCHEMBL20840195 | 0.74 | MEN1 (0.35) | MEN1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL24985404 | 0.73 | OPRL1 (0.44) | KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL29232426 | 0.72 | OPRL1 (0.43) | KDM4EALDH1A1HPGD | |
| SCHEMBL5014657 | 0.72 | SLC6A4 (0.35) | GABRA1GABRB2KDM4EALDH1A1MAPT | |
| SCHEMBL12721704 | 0.72 | MEN1 (0.36) | MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL6990236 | 0.72 | TSHR (0.35) | MEN1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL19771973 | 0.72 | NOS3 (0.42) | MAOAMAOBTSHRS1PR1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |