Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.35 |
| ▸ | HTR2A | P28223 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015048 | 0.87 | SLC6A4 (0.36) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL1251782 | 0.80 | SLC6A4 (0.43) | SLC6A4HTR2AKCNH2ALDH1A1SLC6A2 | |
| SCHEMBL5022876 | 0.74 | ALDH1A1 (0.39) | ALDH1A1GABRA1GABRB2 | |
| SCHEMBL6572888 | 0.72 | ALDH1A1 (0.61) | ALDH1A1GABRA1GABRB2GAA | |
| SCHEMBL22863402 | 0.72 | GABRA1 (0.34) | ALDH1A1GABRA1GABRB2 | |
| SCHEMBL23387413 | 0.72 | GABRA1 (0.52) | ALDH1A1GABRA1GABRB2GAAMAPT | |
| SCHEMBL10019203 | 0.72 | LMNA (0.39) | ALDH1A1GABRA1GABRB2GAA | |
| SCHEMBL15382005 | 0.72 | GABRA1 (0.48) | SLC6A4HTR2AKCNH2ALDH1A1GABRA1 | |
| SCHEMBL2683313 | 0.72 | CYP1A2 (0.37) | ALDH1A1GABRA1GABRB2 | |
| SCHEMBL14036804 | 0.72 | MEN1 (0.34) | ALDH1A1GABRA1GABRB2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |