Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064783 | 0.83 | LRRK2 (0.34) | CHRM3LRRK2CXCR3 | |
| SCHEMBL14420993 | 0.82 | CHRM3 (0.37) | CHRM3LRRK2 | |
| SCHEMBL24311780 | 0.80 | LRRK2 (0.33) | CHRM3LRRK2 | |
| SCHEMBL14417082 | 0.79 | ACHE (0.37) | CHRM3CXCR3 | |
| SCHEMBL20464460 | 0.78 | LRRK2 (0.38) | CHRM3LRRK2CXCR3AR | |
| SCHEMBL24146803 | 0.77 | LRRK2 (0.32) | CHRM3LRRK2 | |
| SCHEMBL14037161 | 0.72 | LRRK2 (0.33) | LRRK2 | |
| SCHEMBL4784805 | 0.72 | — | — | |
| SCHEMBL14417139 | 0.68 | LRRK2 (0.34) | LRRK2 | |
| SCHEMBL31728416 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141011-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | AMIRA PHARMACEUTICALS, INC. (US) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008137609-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | AMIRA PHARMACEUTICALS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| US-20070225285-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | AMIRA PHARMACEUTICALS, INC. (US) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225285-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | ALOX5, ALOX15B, ALOX15 | CHRM3 4098/4885LRRK2 2925/4885CXCR3 2067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.