Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PROC | P04070 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14040501 | 0.82 | MMP2 (0.47) | F10KMT2AMMP2MMP9 | |
| SCHEMBL5881800 | 0.82 | MMP2 (0.47) | F10KMT2AMMP2MMP9 | |
| SCHEMBL27470210 | 0.80 | F10 (0.51) | F10L3MBTL1PLGPROCALDH1A1 | |
| SCHEMBL4756093 | 0.75 | MMP2 (0.50) | MMP2MMP9 | |
| SCHEMBL12997805 | 0.73 | F10 (0.61) | F10PLGPROCKMT2AALDH1A1 | |
| SCHEMBL2700592 | 0.73 | F10 (0.61) | F10PLGPROCKMT2AALDH1A1 | |
| SCHEMBL4703108 | 0.73 | ALDH1A1 (0.48) | L3MBTL1KMT2AALDH1A1SMN1; SMN2MMP2 | |
| SCHEMBL4703238 | 0.73 | ALDH1A1 (0.48) | L3MBTL1KMT2AALDH1A1SMN1; SMN2MMP2 | |
| SCHEMBL14040571 | 0.73 | ALDH1A1 (0.48) | L3MBTL1KMT2AALDH1A1SMN1; SMN2MMP2 | |
| SCHEMBL3683615 | 0.71 | KMT2A (0.69) | L3MBTL1KMT2AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444202-B1 | NOVEL METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-10-15 | — | — | EP | disclosed |