Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84404 | 0.78 | KDM4E (0.46) | ALDH1A1TSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL14041781 | 0.74 | TERT (0.39) | CHRNB2CHRNA4ALDH1A1TSHRMAPK1 | |
| SCHEMBL725480 | 0.73 | PRMT5 (0.34) | ALDH1A1HTTSMN1; SMN2MEN1HPGD | |
| SCHEMBL13436334 | 0.73 | CHRNB2 (0.32) | CHRNB2CHRNA4CYP3A4 | |
| SCHEMBL30665750 | 0.72 | SMN1; SMN2 (0.53) | CHRNB2CHRNA4ALDH1A1TSHRMAPK1 | |
| SCHEMBL13969513 | 0.72 | CHRNB2 (0.38) | CHRNB2CHRNA4ALDH1A1TSHRMAPK1 | |
| SCHEMBL748189 | 0.72 | SMN1; SMN2 (0.53) | CHRNB2CHRNA4ALDH1A1TSHRMAPK1 | |
| SCHEMBL28361799 | 0.71 | PRMT5 (0.33) | ALDH1A1HTTSMN1; SMN2MEN1HPGD | |
| SCHEMBL10053135 | 0.71 | ALDH1A1 (0.55) | ALDH1A1TSHRMAPK1CYP3A4L3MBTL1 | |
| SCHEMBL23260180 | 0.69 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121592-A2 | ACETYL COENZYME A CARBOXYLASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-09 | — | — | WO | disclosed |