Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.55 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14041986 | 0.84 | GSTO1 (0.51) | ADORA3RAB9AKDM4EALDH1A1MAPK1 | |
| SCHEMBL2753298 | 0.79 | ADORA3 (1.00) | ADORA3RAB9AKDM4EALDH1A1MAPK1 | |
| SCHEMBL1881014 | 0.79 | ADORA3 (0.82) | ADORA3RAB9AKDM4EALDH1A1MAPK1 | |
| SCHEMBL12301211 | 0.78 | ADORA3 (0.76) | ADORA3RAB9AKDM4EALDH1A1MAPK1 | |
| SCHEMBL16607129 | 0.77 | ADORA3 (0.75) | ADORA3RAB9AKDM4EALDH1A1MAPK1 | |
| SCHEMBL18456565 | 0.76 | ALDH1A1 (0.68) | ADORA3RAB9AKDM4EALDH1A1MAPK1 | |
| SCHEMBL18425979 | 0.76 | MAPT (0.81) | ADORA3RAB9AKDM4EALDH1A1MAPK1 | |
| SCHEMBL14041816 | 0.75 | ADORA3 (0.68) | ADORA3RAB9AKDM4EALDH1A1MAPK1 | |
| SCHEMBL20462770 | 0.75 | RAB9A (0.68) | ADORA3RAB9AKDM4EALDH1A1MAPK1 | |
| SCHEMBL18456653 | 0.75 | ALDH1A1 (0.67) | ADORA3RAB9AKDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | claimed |
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | disclosed |