Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.54 |
| ▸ | CA9 | Q16790 | 15/20 | 0.54 |
| ▸ | CA1 | P00915 | 15/20 | 0.54 |
| ▸ | CA12 | O43570 | 13/20 | 0.54 |
| ▸ | CA5A | P35218 | 9/20 | 0.54 |
| ▸ | CA7 | P43166 | 9/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 9/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.54 |
| ▸ | CA6 | P23280 | 6/20 | 0.54 |
| ▸ | CA4 | P22748 | 6/20 | 0.54 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.54 |
| ▸ | CA3 | P07451 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091350 | 0.84 | CA2 (0.56) | CA2CA9CA1CA12CA5A | |
| SCHEMBL8248221 | 0.77 | ALDH1A1 (0.62) | CA2CA9CA1CA12CA5A | |
| SCHEMBL1790668 | 0.77 | ALDH1A1 (0.62) | CA2CA9CA1CA12CA5A | |
| SCHEMBL1186051 | 0.77 | ALDH1A1 (0.62) | CA2CA9CA1CA12CA5A | |
| SCHEMBL202948 | 0.77 | CA2 (0.81) | CA2CA9CA1CA12CA5A | |
| Hydrochloric Acid SCHEMBL2352018 | 0.76 | ALDH1A1 (0.60) | CA2CA9CA1CA12CA5A | |
| SCHEMBL7440861 | 0.75 | CA2 (0.52) | CA2CA9CA1CA12CA5A | |
| SCHEMBL84516 | 0.74 | CA2 (0.68) | CA2CA9CA1CA12CA5A | |
| SCHEMBL30003292 | 0.74 | CA2 (0.54) | CA2CA9CA1CA12CA5A | |
| SCHEMBL6760395 | 0.74 | ALDH1A1 (0.53) | CA2CA9CA1CA12CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130570-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |