Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.54 |
| ▸ | CA9 | Q16790 | 14/20 | 0.54 |
| ▸ | CA12 | O43570 | 12/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 13/20 | 0.52 |
| ▸ | CA5A | P35218 | 8/20 | 0.52 |
| ▸ | CA7 | P43166 | 8/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 8/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.52 |
| ▸ | CA6 | P23280 | 6/20 | 0.52 |
| ▸ | CA4 | P22748 | 6/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3457899 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TSHR | |
| SCHEMBL202948 | 0.79 | CA2 (0.81) | CA2CA9CA12ALDH1A1CA1 | |
| SCHEMBL11698441 | 0.78 | F2 (0.43) | CA2ALDH1A1TSHR | |
| SCHEMBL3091350 | 0.76 | CA2 (0.56) | CA2CA9CA12ALDH1A1CA1 | |
| Sulfanilamide SCHEMBL17782005 | 0.76 | CA2 (0.81) | CA2CA9CA12ALDH1A1CA1 | |
| SCHEMBL17463073 | 0.76 | TRPV4 (0.52) | CA2CA9CA12ALDH1A1CA1 | |
| SCHEMBL17289163 | 0.76 | ENPP2 (0.50) | — | |
| SCHEMBL84516 | 0.76 | CA2 (0.68) | CA2CA9CA12ALDH1A1CA1 | |
| SCHEMBL31046935 | 0.76 | CA2 (0.54) | CA2CA9CA12ALDH1A1CA1 | |
| SCHEMBL8248221 | 0.74 | ALDH1A1 (0.62) | CA2CA9CA12ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11471455-B2 | Compounds and compositions for treating conditions associated with APJ receptor activity | ANNAPURNA BIO, INC. (US) | 2022-10-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11471455-B2 | Compounds and compositions for treating conditions associated with APJ receptor activity | APLNR, AGTR1, AGTR2 | CA2 962/4885CA9 635/4885CA12 2101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.