Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | PLEC | Q15149 | 1/20 | 0.72 |
| ▸ | ALPL | P05186 | 1/20 | 0.60 |
| ▸ | ALPI | P09923 | 1/20 | 0.60 |
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | QPCT | Q16769 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14044262 | 0.86 | USP2 (0.77) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL21945707 | 0.86 | USP2 (0.59) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL9883329 | 0.84 | USP2 (0.77) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL940682 | 0.84 | MEN1 (1.00) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL10167876 | 0.83 | MEN1 (0.72) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL12637647 | 0.83 | USP2 (0.72) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL16231516 | 0.82 | USP2 (0.64) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL7824274 | 0.82 | USP2 (0.77) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL10082363 | 0.82 | USP2 (0.73) | USP2MEN1KMT2APOLBATM | |
| SCHEMBL16169467 | 0.81 | MEN1 (0.68) | USP2MEN1KMT2APOLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160176942-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS PLC (GB) | 2016-06-23 | — | — | US | disclosed |
| US-9295729-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS PLC (GB) | 2016-03-29 | — | — | US | disclosed |
| US-20150031861-A1 | Chemical Modification of Antibodies | UCL BUSINESS PLC (GB) | 2015-01-29 | — | — | US | disclosed |
| US-20130209361-A1 | PROCESS FOR PRODUCING RADIOHALOGENATED BIOCONJUGATES AND PRODUCTS THEREOF | UCL BUSINESS PLC (GB) | 2013-08-15 | — | — | US | disclosed |
| US-20120190124-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS LTD (GB) | 2012-07-26 | — | — | US | disclosed |
| US-20120190579-A1 | Functionalisation of Solid Substrates | UCL BUSINESS PLC (GB) | 2012-07-26 | — | — | US | disclosed |
| US-20120077863-A1 | GUANIDINO-SUBSTITUTED BI-AND POLYPHENYLS AS SMALL MOLECULE CARRIERS | UCL BUSINESS PLC (GB) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190124-A1 | Reversible Covalent Linkage of Functional Molecules | F12, F13A1, F2 | USP2 2243/4885MEN1 1641/4885KMT2A 1777/4885 |
| US-20120190579-A1 | Functionalisation of Solid Substrates | XDH, SPR, DAO | USP2 3068/4885MEN1 3443/4885KMT2A 4234/4885 |
| US-20160176942-A1 | Reversible Covalent Linkage of Functional Molecules | F12, F13A1, F2 | USP2 2243/4885MEN1 1641/4885KMT2A 1777/4885 |
| US-20130209361-A1 | PROCESS FOR PRODUCING RADIOHALOGENATED BIOCONJUGATES AND PRODUCTS THEREOF | QPCT, CBR3, SSTR5 | USP2 892/4885MEN1 495/4885KMT2A 3205/4885 |
| US-20150031861-A1 | Chemical Modification of Antibodies | PTMS, FCGRT, PDIA5 | USP2 705/4885MEN1 2404/4885KMT2A 1035/4885 |
| US-20120077863-A1 | GUANIDINO-SUBSTITUTED BI-AND POLYPHENYLS AS SMALL MOLECULE CARRIERS | CFTR, GNB1, GMPS | USP2 4148/4885MEN1 2090/4885KMT2A 4450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.