Ethyl Acetate

Ethyl Acetate

SCHEMBL1404464

CCOC(C)=O.Nc1nc2[nH]cnc2c(=O)n1Cl

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.37
GAA P10253 4/20 0.37
HSD17B10 Q99714 2/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
KDM5B Q9UGL1 2/20 0.35
LMNA P02545 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
MAPK1 P28482 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CSNK1D P48730 1/20 0.34
ALDH1A1 P00352 4/20 0.33
PDE4A P27815 2/20 0.33
PDE4B Q07343 2/20 0.33
PDE4C Q08493 2/20 0.33
PDE4D Q08499 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
BRAF P15056 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20576 0.83 PNP (0.34) LMNAPDE4APDE4BPDE4CPDE4D
Adenine SCHEMBL28145525 0.73 TP53 (0.40) KDM4EGAAHSD17B10HPGDRAB9A
SCHEMBL218666 0.72 GDA (0.34) LMNAPDE4APDE4BPDE4CPDE4D
Bromide SCHEMBL8165610 0.71 GDA (0.33) LMNAPDE4APDE4BPDE4CPDE4D
SCHEMBL1767742 0.71 ADORA2A (0.39) PDE4APDE4BPDE4CPDE4D
SCHEMBL874734 0.71 ADORA2A (0.45) PDE4APDE4BPDE4CPDE4D
SCHEMBL473734 0.71 ADORA2A (0.32) KDM4EGAAHSD17B10HPGDRAB9A
SCHEMBL7672440 0.70 GAA (0.36) KDM4EGAAHSD17B10HPGDRAB9A
SCHEMBL3072977 0.69 MGMT (0.32) KDM4EGAAKDM5BPDE4APDE4B
SCHEMBL667794 0.69 PDE4A (0.49) HSD17B10HPGDPDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10036066-B2 In situ hybridization detection method DAKO DENMARK A/S (DK) 2018-07-31 US disclosed
US-9598720-B2 Monomeric and polymeric linkers useful for conjugating biological molecules and other substances DAKO DENMARK A/S (DK) 2017-03-21 US disclosed
US-20160273035-A1 IN SITU HYBRIDIZATION DETECTION METHOD DAKO DENMARK A/S (DK) 2016-09-22 US disclosed
EP-1919930-B1 NEW NUCLEIC ACID BASE PAIRS DAKO DENMARK AS (DK) 2016-09-14 EP disclosed
US-9340824-B2 Immunohistochemistry detection method DAKO DENMARK A/S (DK) 2016-05-17 US disclosed
US-9017992-B2 In situ hybridization detection method DAKO DENMARK A/S (DK) 2015-04-28 US disclosed
EP-1910575-B1 IMMUNOHISTOCHEMISTRY DETECTION METHOD DAKO DENMARK AS (DK) 2014-12-10 EP disclosed
US-20140315204-A1 Immunohistochemistry Detection Method DAKO DENMARK A/S (DK) 2014-10-23 US disclosed
US-8741566-B2 Immunohistochemistry and in situ hybridization detection method DAKO DENMARK A/S (DK) 2014-06-03 US disclosed
US-20140080145-A1 Monomeric and Polymeric Linkers Useful For Conjugating Biological Molecules and Other Substances DAKO DENMARK A/S (DK) 2014-03-20 US disclosed
EP-1919930-A2 NEW NUCLEIC ACID BASE PAIRS Dako Denmark A/S (DK) 2008-05-14 EP disclosed
EP-1920073-A2 METHOD OF SIMULTANEOUSLY VISUALIZING MULTIPLE BIOLOGICAL TARGETS Dako Denmark A/S (DK) 2008-05-14 EP disclosed
EP-1910575-A2 IMMUNOHISTOCHEMISTRY DETECTION METHOD Dako Denmark A/S (DK) 2008-04-16 EP disclosed
EP-1907592-A2 MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES Dako Denmark A/S (DK) 2008-04-09 EP disclosed
WO-2007031874-A9 METHOD OF SIMULTANEOUSLY VISUALIZING MULTIPLE BIOLOGICAL TARGETS DAKO DENMARK AS (DK) 2007-05-31 WO disclosed
WO-2007045998-A2 NEW NUCLEIC ACID BASE PAIRS DAKO DENMARK A/S (US) 2007-04-26 WO disclosed
WO-2007031874-A2 METHOD OF SIMULTANEOUSLY VISUALIZING MULTIPLE BIOLOGICAL TARGETS DAKO DENMARK A/S (US) 2007-03-22 WO disclosed
WO-2007026252-A2 IN SITU HYBRIDIZATION DETECTION METHOD DAKO DENMARK A/S (US) 2007-03-08 WO disclosed
WO-2007023390-A2 IMMUNOHISTOCHEMISTRY DETECTION METHOD DAKO DENMARK A/S (US) 2007-03-01 WO disclosed
WO-2007015168-A2 MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES DAKO DENMARK A/S (US) 2007-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140080145-A1 Monomeric and Polymeric Linkers Useful For Conjugating Biological Molecules and Other Substances PCNA, DCLRE1A, TK1 KDM4E 4606/4885GAA 1024/4885HSD17B10 4700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.