SCHEMBL1404493

SCHEMBL1404493

NCCOCCOCCNC(=O)COCC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CA2 P00918 5/20 0.37
NCF1 P14598 1/20 0.35
CA12 O43570 4/20 0.35
CA1 P00915 4/20 0.35
CA4 P22748 4/20 0.35
CA9 Q16790 4/20 0.35
CA14 Q9ULX7 4/20 0.35
POLB P06746 1/20 0.34
TSHR P16473 1/20 0.33
RECQL P46063 1/20 0.33
ENO1 P06733 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL422917 1.00 GLP1R (0.38) GLP1RSMN1; SMN2MEN1KMT2ACA2
SCHEMBL16943973 1.00 GLP1R (0.38) GLP1RSMN1; SMN2MEN1KMT2ACA2
SCHEMBL964367 1.00 GLP1R (0.38) GLP1RSMN1; SMN2MEN1KMT2ACA2
SCHEMBL1257485 0.97 GLP1R (0.41) GLP1RSMN1; SMN2MEN1KMT2ACA2
SCHEMBL30466662 0.97 GLP1R (0.41) GLP1RSMN1; SMN2MEN1KMT2ACA2
SCHEMBL20017289 0.93 MEN1 (0.41) GLP1RSMN1; SMN2MEN1KMT2ACA2
SCHEMBL2743010 0.91 SMN1; SMN2 (0.43) GLP1RSMN1; SMN2MEN1KMT2ACA2
SCHEMBL14453741 0.90 TSHR (0.43) GLP1RSMN1; SMN2TSHRRECQL
SCHEMBL24040332 0.89 MEN1 (0.41) GLP1RSMN1; SMN2MEN1KMT2ACA2
SCHEMBL24518424 0.87 SMN1; SMN2 (0.36) GLP1RSMN1; SMN2MEN1KMT2ACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3620465-B1 IMPROVED METHODS FOR GENERATION, LABELING AND USE OF MHC MULTIMERS DAKO DENMARK AS (DK) 2025-02-19 EP disclosed
US-20240150431-A1 MHC Multimers, Methods for Their Generation, Labeling and Use DAKO DENMARK APS (DK) 2024-05-09 US disclosed
US-20230340039-A1 NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INT (DE) 2023-10-26 US disclosed
US-20230270867-A1 CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME PINOTBIO, INC. (KR) 2023-08-31 US disclosed
EP-4192853-A1 SOLUBLE NPY2 RECEPTOR AGONISTS Boehringer Ingelheim International GmbH (DE) 2023-06-14 EP disclosed
EP-4058047-A1 NPY2 RECEPTOR AGONISTS Boehringer Ingelheim International GmbH (DE) 2022-09-21 EP disclosed
WO-2021094259-A1 NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2021-05-20 WO disclosed
US-20210139548-A1 NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2021-05-13 US disclosed
US-20190112348-A1 PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES NOVO NORDISK AS (DK) 2019-04-18 US disclosed
US-10259856-B2 Protease stabilized acylated insulin analogues NOVO NORDISK A/S (DK) 2019-04-16 US disclosed
US-20100120054-A1 MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES DAKO DENMARK APS (DK) 2010-05-13 US disclosed
US-20100055761-A1 METHODS, COMPOSITIONS, AND KITS FOR THE SELECTIVE ACTIVATION OF PROTOXINS THROUGH COMBINATORAL TARGETING THE GENERAL HOSPITAL CORPORATION (US) 2010-03-04 US disclosed
US-20100055761-A1 METHODS, COMPOSITIONS, AND KITS FOR THE SELECTIVE ACTIVATION OF PROTOXINS THROUGH COMBINATORAL TARGETING THE GENERAL HOSPITAL CORPORATION (US) 2010-03-04 US disclosed
US-20100055761-A1 METHODS, COMPOSITIONS, AND KITS FOR THE SELECTIVE ACTIVATION OF PROTOXINS THROUGH COMBINATORAL TARGETING THE GENERAL HOSPITAL CORPORATION (US) 2010-03-04 US disclosed
WO-2009115469-A1 PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES NOVO NORDISK A/S (DK) 2009-09-24 WO disclosed
EP-2046375-A2 METHODS, COMPOSITIONS, AND KITS FOR THE SELECTIVE ACTIVATION OF PROTOXINS THROUGH COMBINATORIAL TARGETING The General Hospital Corporation (US) 2009-04-15 EP disclosed
WO-2009022006-A1 INSULINS WITH AN ACYL MOIETY COMPRISING REPEATING UNITS OF ALKYLENE GLYCOL CONTAINING AMINO ACIDS NOVO NORDISK A/S (DK) 2009-02-19 WO disclosed
EP-1907592-A2 MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES Dako Denmark A/S (DK) 2008-04-09 EP disclosed
WO-2008011157-A2 METHODS, COMPOSITIONS, AND KITS FOR THE SELECTIVE ACTIVATION OF PROTOXINS THROUGH COMBINATORIAL TARGETING THE GENERAL HOSPITAL CORPORATION (US) 2008-01-24 WO disclosed
WO-2007015168-A2 MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES DAKO DENMARK A/S (US) 2007-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270867-A1 CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME SLC46A1, SLC47A1, FOLR1 GLP1R 2794/4885SMN1; SMN2 4568/4885MEN1 1030/4885
US-20210139548-A1 NPY2 RECEPTOR AGONISTS NPY2R, NPY1R, NPY5R GLP1R 6/4885SMN1; SMN2 1118/4885MEN1 1347/4885
US-20240150431-A1 MHC Multimers, Methods for Their Generation, Labeling and Use MICA, CD74, HLA-DRB1 GLP1R 4718/4885SMN1; SMN2 2853/4885MEN1 2127/4885
US-20230340039-A1 NPY2 RECEPTOR AGONISTS NPY2R, NPY1R, NPY5R GLP1R 6/4885SMN1; SMN2 1118/4885MEN1 1347/4885
US-20190112348-A1 PROTEASE STABILIZED, ACYLATED INSULIN ANALOGUES IAPP, IDE, LIPE GLP1R 84/4885SMN1; SMN2 1083/4885MEN1 535/4885
US-10259856-B2 Protease stabilized acylated insulin analogues IAPP, IDE, LIPE GLP1R 54/4885SMN1; SMN2 1218/4885MEN1 560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.