Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | PPIB | P23284 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620068 | 0.86 | AGTR2 (0.37) | OPRM1OPRL1KMT2AOPRD1ALDH1A1 | |
| SCHEMBL10172489 | 0.81 | DDB1 (0.40) | OPRM1OPRL1ALDH1A1TSHRNPC1 | |
| SCHEMBL14019929 | 0.79 | NPSR1 (0.40) | PPIBKMT2APKMLMNAHTT | |
| SCHEMBL307624 | 0.79 | KMT2A (0.42) | OPRM1OPRL1KMT2APKMLMNA | |
| SCHEMBL307698 | 0.76 | OPRK1 (0.47) | PPIBKMT2APKMLMNAHTT | |
| SCHEMBL966680 | 0.74 | OPRM1 (0.51) | OPRM1OPRL1FASNKMT2AALDH1A1 | |
| SCHEMBL2605839 | 0.74 | SPHK1 (0.47) | OPRM1OPRL1KMT2AALDH1A1LMNA | |
| SCHEMBL12561282 | 0.73 | SMN1; SMN2 (0.41) | OPRM1OPRL1KMT2AALDH1A1LMNA | |
| SCHEMBL2754184 | 0.71 | ALDH1A1 (0.45) | OPRM1OPRL1PPIBFASNKMT2A | |
| SCHEMBL2605743 | 0.70 | ALDH1A1 (0.54) | PPIBKMT2AALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255155-A1 | KINASE INHIBITORS AND USES THEREOF | METHLYGENE INC. (CA) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255155-A1 | KINASE INHIBITORS AND USES THEREOF | ABL1, MAP3K20, MAP3K1 | OPRM1 4750/4885OPRL1 4021/4885PPIB 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.