Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019868 | 0.83 | EPHX1 (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL2605729 | 0.81 | RIPK1 (0.50) | CA1ALDH1A1KDM4EMAPTALOX12 | |
| SCHEMBL14045184 | 0.79 | HPGD (0.49) | ALDH1A1SMN1; SMN2HPGDGAAMEN1 | |
| SCHEMBL14045079 | 0.79 | CA1 (0.51) | CA1CA9ALDH1A1KDM4EMAPT | |
| SCHEMBL2605728 | 0.76 | MEN1 (0.57) | ALDH1A1MAPTSMN1; SMN2HPGDMEN1 | |
| SCHEMBL14045187 | 0.75 | HTT (0.41) | CA1CA9ALDH1A1KDM4EMAPT | |
| SCHEMBL10172594 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MAPTALOX12SMN1; SMN2LMNA | |
| SCHEMBL3620889 | 0.71 | KDM4E (0.43) | ALDH1A1KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL25673396 | 0.71 | GABRA1 (0.43) | ALDH1A1MAPTHPGDGAAHTT | |
| SCHEMBL3618346 | 0.70 | BCAT2 (0.54) | KDM4EMAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255155-A1 | KINASE INHIBITORS AND USES THEREOF | METHLYGENE INC. (CA) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255155-A1 | KINASE INHIBITORS AND USES THEREOF | ABL1, MAP3K20, MAP3K1 | CA1 4067/4885CA9 2690/4885ALDH1A1 3553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.