Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 4/20 | 0.44 |
| ▸ | COPS5 | Q92905 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698452 | 0.77 | PSMD14 (0.44) | PSMD14COPS5KDM4ENPC1ALDH1A1 | |
| SCHEMBL29975471 | 0.77 | BACE1 (0.40) | PSMD14COPS5KDM4ENPC1ABCB1 | |
| SCHEMBL3718782 | 0.77 | KDM4E (0.62) | PSMD14COPS5KDM4EABCB1ABCG2 | |
| SCHEMBL31062026 | 0.77 | KDM4E (0.44) | PSMD14COPS5KDM4ENPC1ABCB1 | |
| SCHEMBL12487794 | 0.77 | KDM4E (0.44) | PSMD14COPS5KDM4ENPC1ABCB1 | |
| SCHEMBL14923574 | 0.77 | KDM4E (0.38) | PSMD14COPS5KDM4ENPC1ABCB1 | |
| SCHEMBL1666214 | 0.77 | TET2 (0.44) | PSMD14COPS5KDM4ENPC1ABCB1 | |
| SCHEMBL4157022 | 0.77 | SMN1; SMN2 (0.42) | PSMD14COPS5KDM4ENPC1ABCB1 | |
| SCHEMBL22333784 | 0.73 | CCR1 (0.62) | PSMD14COPS5KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL23479217 | 0.73 | KDM4E (0.38) | PSMD14COPS5KDM4ENPC1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255359-A1 | Novel Chemical Process For the Synthesis of Quinoline Compounds | ROIVANT NEUROSCIENCES LTD. (BM) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255359-A1 | Novel Chemical Process For the Synthesis of Quinoline Compounds | QDPR, NDUFS3, NQO2 | PSMD14 2767/4885COPS5 1486/4885KDM4E 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.