Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29897114 | 0.82 | CYP1A2 (0.56) | ABL1RIN1CYP1A2ALDH1A1LMNA | |
| SCHEMBL14024400 | 0.80 | TK1 (0.42) | CYP1A2LMNASMN1; SMN2POLBRNASE1 | |
| SCHEMBL26916163 | 0.77 | P2RX4 (0.41) | ALDH1A1HPGDKDM4EIDO1POLB | |
| SCHEMBL23797137 | 0.76 | ABL1 (0.46) | ABL1RIN1CYP1A2ALDH1A1LMNA | |
| SCHEMBL6632471 | 0.76 | ABL1 (0.46) | ABL1RIN1CYP1A2ALDH1A1LMNA | |
| SCHEMBL5013964 | 0.76 | ABL1 (0.46) | ABL1RIN1CYP1A2ALDH1A1LMNA | |
| SCHEMBL12062406 | 0.75 | KDM4E (0.45) | ALDH1A1HPGDKDM4ESMN1; SMN2POLB | |
| SCHEMBL6330943 | 0.74 | ABL1 (0.44) | ABL1RIN1CYP1A2ALDH1A1LMNA | |
| SCHEMBL9351697 | 0.71 | ABL1 (0.42) | ABL1RIN1CYP1A2ALDH1A1LMNA | |
| SCHEMBL9351701 | 0.71 | ABL1 (0.42) | ABL1RIN1CYP1A2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269476-A1 | Molecules and methods for nucleic acid sequencing | HELICOS BIOSCIENCES CORPORATION (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080103058-A1 | Molecules and methods for nucleic acid sequencing | HELICOS BIOSCIENCES CORPORATION (US) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103058-A1 | Molecules and methods for nucleic acid sequencing | POLRMT, RNGTT, POLM | ABL1 164/4885RIN1 4191/4885CYP1A2 2401/4885 |
| US-20080269476-A1 | Molecules and methods for nucleic acid sequencing | POLRMT, RNGTT, POLM | ABL1 164/4885RIN1 4191/4885CYP1A2 2401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.