Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALB | P02768 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013964 | 1.00 | ABL1 (0.46) | ABL1RIN1LMNAALBALDH1A1 | |
| SCHEMBL23797137 | 0.83 | ABL1 (0.46) | ABL1RIN1LMNAALBALDH1A1 | |
| SCHEMBL6330943 | 0.81 | ABL1 (0.44) | ABL1RIN1LMNAALBALDH1A1 | |
| SCHEMBL6744346 | 0.77 | ABL1 (0.41) | ABL1RIN1LMNAALBALDH1A1 | |
| SCHEMBL6744345 | 0.77 | ABL1 (0.41) | ABL1RIN1LMNAALBALDH1A1 | |
| SCHEMBL1421772 | 0.77 | LMNA (0.42) | ABL1RIN1LMNAALBALDH1A1 | |
| SCHEMBL22080061 | 0.76 | ABL1 (0.45) | ABL1RIN1LMNAALBALDH1A1 | |
| SCHEMBL25813255 | 0.76 | ABL1 (0.45) | ABL1RIN1LMNAALBALDH1A1 | |
| SCHEMBL14045693 | 0.76 | ABL1 (0.55) | ABL1RIN1LMNAALBALDH1A1 | |
| SCHEMBL4501110 | 0.76 | ALDH1A1 (0.41) | ABL1RIN1LMNAALBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012115578-A1 | SYNTHESIS OF FLG | MEDIVIR AB (SE) | 2012-08-30 | — | — | WO | disclosed |
| EP-1387850-A2 | ANTIVIRAL NUCLEOSIDES | Kumar, Rakesh (CA) | 2004-02-11 | — | — | EP | disclosed |
| WO-2002094844-A2 | ANTIVIRAL NUCLEOSIDES | KUMAR RAKESH (CA) | 2002-11-28 | — | — | WO | disclosed |
| WO-1990003978-A1 | 5-HALOGENO-3'-FLUORO-2',3'-DIDEOXYURIDINE COMPOUNDS AND THEIR THERAPEUTIC APPLICATION | STICHTING REGA VZW (BE) | 1990-04-19 | — | — | WO | disclosed |
| EP-0317128-A2 | Anti-HIV Pyrimidine Nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-05-24 | — | — | EP | disclosed |