Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | FABP4 | P15090 | 3/20 | 0.54 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.54 |
| ▸ | CMA1 | P23946 | 6/20 | 0.47 |
| ▸ | CTSG | P08311 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14664244 | 0.86 | MEN1 (0.52) | MEN1KMT2AATMFABP4FABP5 | |
| SCHEMBL14021860 | 0.85 | MEN1 (0.51) | MEN1KMT2AATMTACR1OPRM1 | |
| SCHEMBL13240513 | 0.84 | MEN1 (0.50) | MEN1KMT2AATMFABP4FABP5 | |
| SCHEMBL11094129 | 0.84 | MEN1 (0.58) | MEN1KMT2AATMCMA1APEX1 | |
| SCHEMBL1405053 | 0.83 | TNF (0.59) | MEN1KMT2AATML3MBTL1TACR1 | |
| SCHEMBL9385716 | 0.83 | MEN1 (0.49) | MEN1KMT2AATML3MBTL1TACR1 | |
| SCHEMBL507642 | 0.83 | MEN1 (0.60) | MEN1KMT2AATMHTTL3MBTL1 | |
| SCHEMBL508219 | 0.83 | MEN1 (0.57) | MEN1KMT2AATMAPEX1HTT | |
| SCHEMBL10540522 | 0.83 | MEN1 (0.54) | MEN1KMT2AATML3MBTL1TACR1 | |
| SCHEMBL6217963 | 0.82 | APEX1 (0.67) | MEN1KMT2AATMAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11214551-B2 | One pot synthesis of 4-(1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)butanoic acid, a key intermediate of zilpaterol | RA CHEM PHARMA LIMITED (IN) | 2022-01-04 | — | — | US | disclosed |
| US-20210238146-A1 | ONE POT SYNTHESIS OF 4-(1,2-DIHYDRO-2-OXOBENZO[D]IMIDAZOL-3-YL)BUTANOIC ACID, A KEY INTERMEDIATE OF ZILPATEROL | COHANCE LIFESCIENCES LIMITED (IN) | 2021-08-05 | — | — | US | disclosed |
| EP-2935275-B9 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INT BV (NL) | 2017-10-11 | — | — | EP | disclosed |
| US-9630967-B2 | Process for making zilpaterol | INTERVET INC. (US) | 2017-04-25 | — | — | US | disclosed |
| EP-2935275-B1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INT BV (NL) | 2017-03-08 | — | — | EP | disclosed |
| EP-2535340-B1 | Process for making zilpaterol and salts thereof | INTERVET INT BV (NL) | 2016-04-27 | — | — | EP | disclosed |
| US-20150315195-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INC. (US) | 2015-11-05 | — | — | US | disclosed |
| EP-2142553-B1 | PROCESSES FOR MAKING ZILPATEROL AND SALTS THEREOF | INTERVET INT BV (NL) | 2015-08-19 | — | — | EP | disclosed |
| EP-2109614-B1 | ENANTIOSELECTIVE SYNTHESIS OF 6-AMINO-7-HYDROXY-4, 5, 6, 7-TETRAHYDRO-IMIDAZO [4, 5, 1-JK][1]-BENZAZEPIN-2 [1H]-ONE AND ZILPATEROL | INTERVET INT BV (NL) | 2014-08-06 | — | — | EP | disclosed |
| WO-2014095822-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INTERNATIONAL B.V. (NL) | 2014-06-26 | — | — | WO | disclosed |
| WO-2008092924-A1 | ENANTIOSELECTIVE SYNTHESIS OF 6-AMINO-7-HYDROXY-4, 5, 6, 7-TETRAHYDRO-IMIDAZO [4, 5, 1-JK] [1] -BENZAZEPIN-2 [1H] -ONE AND ZILPATEROL | INTERVET INTERNATIONAL B.V. (NL) | 2008-08-07 | — | — | WO | disclosed |
| US-20080161288-A1 | COMPOUNDS | PFIZER INC. | 2008-07-03 | — | — | US | disclosed |
| US-20080161288-A1 | COMPOUNDS | PFIZER INC. | 2008-07-03 | — | — | US | disclosed |
| US-20080161288-A1 | COMPOUNDS | PFIZER INC. | 2008-07-03 | — | — | US | disclosed |
| WO-2008050207-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANABOLIC AGENTS FOR LIVESTOCK ANIMALS | PFIZER LIMITED (GB) | 2008-05-02 | — | — | WO | disclosed |
| US-20080103130-A1 | 7-hydroxy-6-{[1-methyl-3-(1,3-thiazol-5-yl)propyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one; agonists at the beta-2 adrenoceptor; feed additives for livestock animals; improving meat yield or meat quality | PFIZER LIMITED (GB) | 2008-05-01 | — | — | US | disclosed |
| US-20080103130-A1 | 7-hydroxy-6-{[1-methyl-3-(1,3-thiazol-5-yl)propyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one; agonists at the beta-2 adrenoceptor; feed additives for livestock animals; improving meat yield or meat quality | PFIZER LIMITED (GB) | 2008-05-01 | — | — | US | disclosed |
| US-20080103130-A1 | 7-hydroxy-6-{[1-methyl-3-(1,3-thiazol-5-yl)propyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one; agonists at the beta-2 adrenoceptor; feed additives for livestock animals; improving meat yield or meat quality | PFIZER LIMITED (GB) | 2008-05-01 | — | — | US | disclosed |
| WO-2008044127-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANABOLIC AGENTS FOR LIVESTOCK ANIMALS | PFIZER LIMITED (GB) | 2008-04-17 | — | — | WO | disclosed |
| EP-0107569-A1 | 6-Amino-7-hydroxy-4,5,6,7-tetrahydroimidazo(4,5,1-j,k)(1)benzazepin-2(1H)-one derivatives, their salts, their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1984-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103130-A1 | 7-hydroxy-6-{[1-methyl-3-(1,3-thiazol-5-yl)propyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one; agonists at the beta-2 adrenoceptor; feed additives for livestock animals; improving meat yield or meat quality | ADRB2, ADRB1, ADRA2C | MEN1 4157/4885KMT2A 1311/4885ATM 1871/4885 |
| US-20210238146-A1 | ONE POT SYNTHESIS OF 4-(1,2-DIHYDRO-2-OXOBENZO[D]IMIDAZOL-3-YL)BUTANOIC ACID, A KEY INTERMEDIATE OF ZILPATEROL | CYP51A1, MED1, AZI2 | MEN1 3073/4885KMT2A 967/4885ATM 4819/4885 |
| US-11214551-B2 | One pot synthesis of 4-(1,2-dihydro-2-oxobenzo[d]imidazol-3-yl)butanoic acid, a key intermediate of zilpaterol | CYP51A1, MED1, AZI2 | MEN1 3073/4885KMT2A 967/4885ATM 4819/4885 |
| US-20080161288-A1 | COMPOUNDS | ADRB2, ADRB1, ADRA2C | MEN1 3848/4885KMT2A 3393/4885ATM 3360/4885 |
| US-20150315195-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | PPIP5K2, PPIA, ITPA | MEN1 3135/4885KMT2A 790/4885ATM 4856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.