Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 12/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404669 | 0.92 | BRAF (0.36) | BRAFGPR142 | |
| SCHEMBL1378336 | 0.90 | LMNA (0.45) | LMNAABL1BRAFL3MBTL1CYP3A4 | |
| SCHEMBL1404811 | 0.89 | BRAF (0.38) | BRAFGPR142 | |
| SCHEMBL1404780 | 0.88 | MEN1 (0.37) | LMNABRAFGPR142 | |
| SCHEMBL1404768 | 0.88 | ABL1 (0.38) | ABL1BRAFGPR142 | |
| SCHEMBL1404576 | 0.87 | BRAF (0.39) | BRAF | |
| SCHEMBL5779078 | 0.86 | BRAF (0.37) | BRAFGPR142 | |
| SCHEMBL1404902 | 0.85 | BRAF (0.36) | BRAFGPR142 | |
| SCHEMBL4471464 | 0.85 | LMNA (0.46) | LMNAABL1BRAFL3MBTL1CYP3A4 | |
| SCHEMBL1404647 | 0.84 | BRAF (0.36) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692116-B1 | 1,2,3-TRIAZOLE AMIDE DERIVATIVES AS INHIBITORS OF CYTOKINE PRODUCTION | BOEHRINGER INGELHEIM PHARMA (US) | 2011-03-09 | — | — | EP | claimed |