Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14048580 | 0.82 | TBXAS1 (0.33) | TBXAS1 | |
| SCHEMBL24297779 | 0.79 | GABRA1 (0.40) | TBXAS1 | |
| SCHEMBL21937576 | 0.79 | ESR1 (0.37) | TBXAS1 | |
| SCHEMBL13713801 | 0.78 | BCL2L1 (0.44) | — | |
| SCHEMBL16078985 | 0.75 | BCKDK (0.42) | — | |
| SCHEMBL8285035 | 0.71 | MCL1 (0.44) | — | |
| SCHEMBL8284901 | 0.71 | APP (0.32) | — | |
| SCHEMBL5196415 | 0.71 | ESR1 (0.43) | — | |
| SCHEMBL17341211 | 0.70 | EPHX2 (0.41) | — | |
| SCHEMBL14048400 | 0.70 | CYP2A6 (0.42) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1632483-B1 | HETEROCYCLIC SUBSTITUTED CARBONYL DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS | AVENTIS PHARMA INC (US) | 2008-10-29 | — | — | EP | disclosed |