Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14344628 | 0.98 | NAAA (0.44) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL14472726 | 0.93 | NAAA (0.40) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL14286142 | 0.89 | HTR2C (0.39) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL14286140 | 0.87 | HTR2C (0.36) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL28718240 | 0.86 | DGKA (0.59) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL21226023 | 0.83 | DGKA (0.47) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL14565821 | 0.83 | DGKA (0.46) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL20512125 | 0.82 | NAAA (0.55) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL20512074 | 0.82 | NAAA (0.55) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL15693101 | 0.82 | NAAA (0.47) | NAAADGKAHTR2CPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-10-02 | — | — | US | disclosed |
| EP-1639029-B1 | BIODEGRADABLE POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | PARN, PARG, POLL | NAAA 197/4885DGKA 1844/4885HTR2C 3755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.